von Gunten Group

Prof. Dr. Stephan von Gunten, MD, PhD, MME

Group members

former Gruppe Huwiler

former Group members

Dr. Quentin Haas
Dr. Kayluz Frias Boligan
Dr. Stefanie Graeter
Dr. Fabiola Schorer
Dr. Christoph Schneider
Dr. Thomas Demoulins, Postdoc (2010-2012)
Dr. Dr. Camilla Jandus, Postdoc (2010-2012)
Dr. Dr. Marc Wehrli, MD Doktorand (2010-2013)  

Our laboratory is interested in molecular mechanisms that control inflammation and cancer. In particular, we focus on protein-carbohydrate interactions in the immune system and on anti-inflammatory effects mediated by Siglec receptors. Siglecs are carbohydrate-binding receptors (lectins) that have recently received particular attention in light of the capacity to mediate cell death, anti-proliferative effects, and inhibition of cellular activities. We recently identified natural autoantibodies within human intravenous immunoglobulin (IVIG) as endogenous Siglec receptor ligands. The group leader Dr. S. von Gunten is a participating investigator at the Consortium of Functional Glycomics (www.functionalglycomics.org), funded by the US National Institutes of Health (NIH), that aims at defining paradigms by which protein-carbohydrate interactions mediate cell communication. Our group has collaborations with scientists and clinicians from many international and local academic institutions, companies and hospitals.


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Mehta, Akul Y; Tilton, Catherine A; Muerner, Lukas; Gunten, Stephan; Heimburg-Molinaro, Jamie; Cummings, Richard D (2024). Reusable glycan microarrays using a microwave assisted wet-erase (MAWE) process. Glycobiology, 34(2) Oxford University Press 10.1093/glycob/cwad091


Plattner, Kevin; Sousa Augusto, Gilles; Muerner, Lukas; von Gunten, Stephan; Jörg, Lukas; Engeroff, Paul; Bachmann, Martin F; Vogel, Monique (2023). IgE glycosylation is essential for the function of omalizumab. Allergy, 78(9), pp. 2546-2549. Wiley 10.1111/all.15748

Démoulins, Thomas; Schulze, Kai; Ebensen, Thomas; Techakriengkrai, Navapon; Nedumpun, Teerawut; Englezou, Pavlos C; Gerber, Markus; Hlushchuk, Ruslan; Toledo, Darien; Djonov, Valentin; von Gunten, Stephan; McCullough, Kenneth C; Liniger, Matthias; Guzmán, Carlos A; Suradhat, Sanipa; Ruggli, Nicolas (2023). Coatsome-replicon vehicles: Self-replicating RNA vaccines against infectious diseases. Nanomedicine : nanotechnology, biology, and medicine, 49(102655), p. 102655. Elsevier 10.1016/j.nano.2023.102655

Zhu, Cui; Potenza, Duilio M; Yang, Yang; Ajalbert, Guillaume; Mertz, Kirsten D; von Gunten, Stephan; Ming, Xiu-Fen; Yang, Zhihong (2023). Role of pulmonary epithelial arginase-II in activation of fibroblasts and lung inflammaging. Aging cell, 22(4), e13790. Wiley 10.1111/acel.13790

Almizraq, Ruqayyah J; Frias Boligan, Kayluz; Lewis, Bonnie J B; Cen, Selena; Whetstone, Heather; Spirig, Rolf; Käsermann, Fabian; Campbell, Ian K; von Gunten, Stephan; Branch, Donald R (2023). Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis. Pharmacology, 108(2), pp. 176-187. Karger 10.1159/000528780

von Gunten, Stephan; Schneider, Christoph; Imamovic, Lejla; Gorochov, Guy (2023). Antibody diversity in IVIG: Therapeutic opportunities for novel immunotherapeutic drugs. Frontiers in immunology, 14, p. 1166821. Frontiers Research Foundation 10.3389/fimmu.2023.1166821


von Achenbach, Caroline; Hevia Hernandez, Giselle; von Gunten, Stephan (2022). The Choice between Intravenous and Subcutaneous Immunoglobulins: Aspects for Consideration. Pharmacology, 107(11-12), pp. 556-563. Karger 10.1159/000527655

Wolf, Babette; Piksa, Mateusz; Beley, Isabelle; Patoux, Agnes; Besson, Thierry; Cordier, Valerie; Voedisch, Bernd; Schindler, Patrick; Stöllner, Daniela; Perrot, Ludovic; von Gunten, Stephan; Brees, Dominique; Kammüller, Michael (2022). Therapeutic antibody glycosylation impacts antigen recognition and immunogenicity. Immunology, 166(3), pp. 380-407. Wiley-Blackwell 10.1111/imm.13481

Gorochov, Guy; von Gunten, Stephan (2022). Diversification of IgA Antibody Specificities by Mild Chemical Modification? Pharmacology, 107(7-8), pp. 339-340. Karger 10.1159/000524041

Haas, Quentin; Markov, Nikita; Muerner, Lukas; Rubino, Viviana; Benjak, Andrej; Haubitz, Monika; Baerlocher, Gabriela M; Ng, Charlotte K Y; Münz, Christian; Riether, Carsten; Ochsenbein, Adrian F; Simon, Hans-Uwe; von Gunten, Stephan (2022). Siglec-7 represents a glyco-immune checkpoint for non-exhausted effector memory CD8+ T cells with high functional and metabolic capacities. Frontiers in immunology, 13, p. 996746. Frontiers Research Foundation 10.3389/fimmu.2022.996746

Angata, Takashi; von Gunten, Stephan; Schnaar, Ronald L.; Varki, Ajit (2022). I-Type Lectins. In: Essentials of Glycobiology. Cold Spring Harbor Laboratory Press 10.1101/glycobiology.4e.35


Lünemann, Jan D; von Gunten, Stephan; Neumann, Harald (2021). Targeting sialylation to treat central nervous system diseases. Trends in Pharmacological Sciences, 42(12), pp. 998-1008. Elsevier 10.1016/j.tips.2021.09.002

Rollenske, Tim; Burkhalter, Sophie; Muerner, Lukas; von Gunten, Stephan; Lukasiewicz, Jolanta; Wardemann, Hedda; Macpherson, Andrew J. (2021). Parallelism of intestinal secretory IgA shapes functional microbial fitness. Nature, 598(7882), pp. 657-661. Springer Nature 10.1038/s41586-021-03973-7

Girousi, Eleftheria; Mürner, Lukas; Parisi, Ludovica; Rihs, Silvia; von Gunten, Stephan; Katsaros, Christos; Degen, Martin (2021). Lack of IRF6 Disrupts Human Epithelial Homeostasis by Altering Colony Morphology, Migration Pattern, and Differentiation Potential of Keratinocytes. Frontiers in cell and developmental biology, 9(718066), p. 718066. Frontiers 10.3389/fcell.2021.718066

Engeroff, Paul; Plattner, Kevin; Storni, Federico; Storni, Federico; Thoms, Franziska; Frias Boligan, Kayluz; Mürner, Lukas; Eggel, Alexander; von Gunten, Stephan; Bachmann, Martin F.; Vogel, Monique (2021). Glycan-specific IgG anti-IgE autoantibodies are protective against allergic anaphylaxis in a murine model. Journal of allergy and clinical immunology, 147(4), pp. 1430-1441. Elsevier 10.1016/j.jaci.2020.11.031

Wang, Junhua; von Gunten, Stephan; Beldi, Guido; Grandgirard, Denis; Leib, Stephen L.; Gottstein, Bruno (2021). Digest the Sugar, Kill the Parasite: A New Experimental Concept in Treating Alveolar Echinococcosis. Pharmacology, 106(1-2), pp. 3-8. Karger 10.1159/000509355

Cummings, Richard D; von Gunten, Stephan (2021). Targeting the Laminated Layer of Echinococcus multilocularis as a Potential Therapeutic Strategy. Pharmacology, 106(1-2), pp. 1-2. Karger 10.1159/000512769

Hugonnet, Marjolaine; Singh, Pushpita; Haas, Quentin; von Gunten, Stephan (2021). The Distinct Roles of Sialyltransferases in Cancer Biology and Onco-Immunology. Frontiers in immunology, 12, p. 799861. Frontiers Research Foundation 10.3389/fimmu.2021.799861


von Gunten, Stephan; Simon, Hans-Uwe (2020). Linking glucocorticoid-induced osteoporosis to osteoimmunology. Cell death & disease, 11(12), p. 1026. Nature Publishing Group 10.1038/s41419-020-03250-x

Yu, Yi; Ladeiras, Diogo; Xiong, Yuyan; Frias Boligan, Kayluz; Liang, Xiujie; von Gunten, Stephan; Hunger, Robert E.; Ming, Xiu-Fen; Yang, Zhihong (2020). Arginase-II promotes melanoma migration and adhesion through enhancing hydrogen peroxide production and STAT3 signaling. Journal of cellular physiology, 235(12), pp. 9997-10011. Wiley 10.1002/jcp.29814

Wehrli, Marc; Schneider, Christoph; Cortinas-Elizondo, Fabiola; Verschoor, Daniëlle; Frias Boligan, Kayluz; Adams, Olivia Joan; Hlushchuk, Ruslan; Engelmann, Christine; Daudel, Fritz; Villiger, Peter M.; Seibold, Frank; Yawalkar, Nikhil; Vonarburg, Cédric; Miescher, Sylvia; Lötscher, Marius; Kaufmann, Thomas; Münz, Christian; Mueller, Christoph; Djonov, Valentin; Simon, Hans-Uwe; ... (2020). IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. Journal of immunology, 205(10), pp. 2640-2648. American Association of Immunologists 10.4049/jimmunol.1900883

Luetscher, Ralph N D; McKitrick, Tanya R; Gao, Chao; Mehta, Akul Y; McQuillan, Alyssa M; Kardish, Robert; Frias Boligan, Kayluz; Song, Xuezheng; Lu, Lenette; Heimburg-Molinaro, Jamie; von Gunten, Stephan; Alter, Galit; Cummings, Richard D (2020). Unique repertoire of anti-carbohydrate antibodies in individual human serum. Scientific reports, 10(1), p. 15436. Springer Nature 10.1038/s41598-020-71967-y

von Gunten, Stephan (2020). Inflamm-Aging: Arginase-II as Stage Setter in Age-Related Adipose Tissue Inflammation. Pharmacology, 105(9-10), pp. 489-490. Karger 10.1159/000510515

Graeter, Stefanie; Simon, Hans-Uwe; von Gunten, Stephan (2020). Granulocyte death mediated by specific antibodies in intravenous immunoglobulin (IVIG). Pharmacological research, 154, p. 104168. Elsevier 10.1016/j.phrs.2019.02.007

Sterlin, Delphine; Fadlallah, Jehane; Adams, Olivia; Fieschi, Claire; Parizot, Christophe; Dorgham, Karim; Rajkumar, Asok; Autaa, Gaëlle; El-Kafsi, Hela; Charuel, Jean-Luc; Juste, Catherine; Jönsson, Friederike; Candela, Thomas; Wardemann, Hedda; Aubry, Alexandra; Capito, Carmen; Brisson, Hélène; Tresallet, Christophe; Cummings, Richard D; Larsen, Martin; ... (2020). Human IgA binds a diverse array of commensal bacteria. Journal of experimental medicine, 217(3) Rockefeller University Press 10.1084/jem.20181635

Sterlin, Delphine; Fadlallah, Jehane; Adams, Olivia; Fieschi, Claire; Parizot, Christophe; Dorgham, Karim; Rajkumar, Asok; Autaa, Gaëlle; El-Kafsi, Hela; Charuel, Jean-Luc; Juste, Catherine; Jönsson, Friederike; Candela, Thomas; Wardemann, Hedda; Aubry, Alexandra; Capito, Carmen; Brisson, Hélène; Tresallet, Christophe; Cummings, Richard D; Larsen, Martin; ... (2020). Correction: Human IgA bind a diverse array of commensal bacteria. Journal of experimental medicine, 217(3) Rockefeller University Press 10.1084/jem.2018163501152020c

Boligan, Kayluz F.; Oechtering, Johanna; Keller, Christian W; Peschke, Benjamin; Rieben, Robert; Bovin, Nicolai; Kappos, Ludwig; Cummings, Richard D; Kuhle, Jens; von Gunten, Stephan; Lünemann, Jan D (2020). Xenogeneic Neu5Gc and self-glycan Neu5Ac epitopes are potential immune targets in MS. Neurology: Neuroimmunology and Neuroinflammation, 7(2) Wolters Kluwer Health 10.1212/NXI.0000000000000676

Spinetti, Thibaud; Meisel, Christian; von Gunten, Stephan; Schefold, Joerg C. (2020). Immune biomarker-based enrichment in sepsis trials. Critical care, 24(1), p. 58. BioMed Central 10.1186/s13054-020-2774-1

von Gunten, Stephan (2020). The Future of Pharmacology: Towards More Personalized Pharmacotherapy and Reverse Translational Research. Pharmacology, 105(1-2), pp. 1-2. Karger 10.1159/000505216

von Gunten, Stephan (2020). Secondary-Type Carbohydrate Modification as a Driver of Epithelial-Mesenchymal Transition and Features of Cancer Stem Cells. Pharmacology, 105(5-6), pp. 244-245. Karger 10.1159/000507003

Graeter, Stefanie; Schneider, Christoph; Verschoor, Daniëlle; von Däniken, Sandro; Seibold, Frank; Yawalkar, Nikhil; Villiger, Peter; Dimitrov, Jordan D; Smith, David F; Cummings, Richard D; Simon, Hans-Uwe; Vassilev, Tchavdar; von Gunten, Stephan (2020). Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils. Frontiers in immunology, 11(973), p. 973. Frontiers Research Foundation 10.3389/fimmu.2020.00973


Jandus, Peter; Frias Boligan, Kayluz; Smith, David F; de Graauw, Elisabeth; Grimbacher, Bodo; Jandus, Camilla; Abd El Hafez, Mai Moustafa Ahmed; Despont, Alain; Bovin, Nicolai; Simon, Dagmar; Rieben, Robert; Simon, Hans-Uwe; Cummings, Richard D; von Gunten, Stephan (2019). The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies (PADs). Blood, 134(22), pp. 1941-1950. American Society of Hematology 10.1182/blood.2019001705

Dorvignit, Denise; Frias Boligan, Kayluz; Relova-Hernández, Ernesto; Clavell, Marilyn; López, Armando; Labrada, Mayrel; Simon, Hans-Uwe; López-Requena, Alejandro; Mesa, Circe; von Gunten, Stephan (2019). Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells. Scientific Reports, 9(1), p. 9921. Nature Publishing Group 10.1038/s41598-019-46148-1

Leviatan Ben-Arye, Shani; Schneider, Christoph; Yu, Hai; Bashir, Salam; Chen, Xi; von Gunten, Stephan; Padler-Karavani, Vered (2019). Differential Recognition of Diet-Derived Neu5Gc-Neoantigens on Glycan Microarrays by Carbohydrate-Specific Pooled Human IgG and IgA Antibodies. Bioconjugate chemistry, 30(5), pp. 1565-1574. American Chemical Society 10.1021/acs.bioconjchem.9b00273

Haas, Quentin; Frias Boligan, Kayluz; Jandus, Camilla; Schneider, Christoph; Simillion, Cedric; Stanczak, Michal A; Haubitz, Monika; Jafari, Morteza; Zippelius, Alfred; Baerlocher, Gabriela M.; Läubli, Heinz; Hunger, Robert E.; Romero, Pedro; Simon, Hans-Uwe; von Gunten, Stephan (2019). Siglec-9 Regulates an Effector Memory CD8 T-cell Subset That Congregates in the Melanoma Tumor Microenvironment. Cancer immunology research, 7(5), pp. 707-718. American Association for Cancer Research 10.1158/2326-6066.CIR-18-0505

Verschoor, Daniëlle; von Gunten, Stephan (2019). Allergy and Atopic Diseases: An Update on Experimental Evidence. International archives of allergy and immunology, 180(4), pp. 235-243. Karger 10.1159/000504439


Basaco, Tais; Pektor, Stefanie; Bermudez, Josue M.; Meneses, Niurka; Heller, Manfred; Galván, José A.; Frias Boligan, Kayluz; Schürch, Stefan; von Gunten, Stephan; Türler, Andreas; Miederer, Matthias (2018). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo. Pharmaceuticals, 11(4) MDPI 10.3390/ph11040132

Stanczak, Michal A; Siddiqui, Shoib S; Trefny, Marcel P; Thommen, Daniela S; Frias Boligan, Kayluz; von Gunten, Stephan; Tzankov, Alexandar; Tietze, Lothar; Lardinois, Didier; Heinzelmann-Schwarz, Viola; von Bergwelt-Baildon, Michael S; Zhang, Wu; Lenz, Heinz-Josef; Han, Younghan; Amos, Christopher I; Syedbasha, Mohammedyaseen; Egli, Adrian; Stenner, Frank; Speiser, Daniel E; Varki, Ajit; ... (2018). Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells. Journal of clinical investigation, 128(11), pp. 4912-4923. American Society for Clinical Investigation 10.1172/JCI120612

Adams, Olivia Joan; Stanczak, Michal A; von Gunten, Stephan; Läubli, Heinz (2018). Targeting sialic acid-Siglec interactions to reverse immune suppression in cancer. Glycobiology, 28(9), pp. 640-647. Oxford University Press 10.1093/glycob/cwx108

Haas, Quentin; Simillion, Cedric André Marie; von Gunten, Stephan (2018). A Cartography of Siglecs and Sialyltransferases in Gynecologic Malignancies: Is There a Road Towards a Sweet Future? Frontiers in oncology, 8, p. 68. Frontiers Research Foundation 10.3389/fonc.2018.00068

Adams, Olivia Joan; von Gunten, Stephan (2018). Recent Advances in Experimental Allergy. International archives of allergy and immunology, 177(4), pp. 281-289. Karger 10.1159/000494440


Späth, Peter Julius; Schneider, Christoph; von Gunten, Stephan (2017). Clinical Use and Therapeutic Potential of IVIG/SCIG, Plasma-Derived IgA or IgM, and Other Alternative Immunoglobulin Preparations. Archivum immunologiae et therapiae experimentalis, 65(3), pp. 215-231. Springer 10.1007/s00005-016-0422-x

Frias Boligan, Kayluz; von Gunten, Stephan (2017). Innate lymphoid cells in asthma: cannabinoids on the balance. Allergy, 72(6), pp. 839-841. Wiley-Blackwell 10.1111/all.13145

Schneider, Christoph; Wicki, Simone; Graeter, Stefanie; Maneva Timcheva, Tankica; Keller, Christian W; Quast, Isaak; Leontyev, Danila; Djoumerska-Alexieva, Iglika K; Käsermann, Fabian; Jakob, Stephan; Dimitrova, Petya A; Branch, Donald R; Cummings, Richard D; Lünemann, Jan D; Kaufmann, Thomas; Simon, Hans-Uwe; von Gunten, Stephan (2017). IVIG regulates the survival of human but not mouse neutrophils. Scientific Reports, 7(1), p. 1296. Nature Publishing Group 10.1038/s41598-017-01404-0

Kouskoura, Thaleia; Katsaros, Christos; von Gunten, Stephan (2017). The Potential Use of Pharmacological Agents to Modulate Orthodontic Tooth Movement (OTM). Frontiers in physiology, 8(67), p. 67. Frontiers Research Foundation 10.3389/fphys.2017.00067

Schneider, Christoph; Illi, Marlies; Lötscher, Marius; Wehrli, Marc; von Gunten, Stephan (2017). Isolation of Antibodies from Human Plasma, Saliva, Breast Milk, and Gastrointestinal Fluid. Methods in molecular biology, 1643, pp. 23-31. Springer 10.1007/978-1-4939-7180-0_3


Quast, Isaak; Keller, Christian W; Weber, Patrick; Schneider, Christoph; von Gunten, Stephan; Lünemann, Jan D (2016). Protection from experimental autoimmune encephalomyelitis by polyclonal IgG requires adjuvant-induced inflammation. Journal of neuroinflammation, 13, p. 42. BioMed Central 10.1186/s12974-016-0506-x

(2016). Protein-carbohydrate interactions in the human immune system (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)

Brönnimann, Daniel; Bouchet, Audrey Michele; Schneider, Christoph; Potez, Marine Therese Charlette; Serduc, Raphaël; Bräuer-Krisch, Elke; Graber, Werner Adrian; von Gunten, Stephan; Laissue, Jean Albert; Djonov, Valentin (2016). Synchrotron microbeam irradiation induces neutrophil infiltration, thrombocyte attachment and selective vascular damage in vivo. Scientific Reports, 6(33601), p. 33601. Nature Publishing Group 10.1038/srep33601

Schorer, Myriam Fabiola; Simon, Dagmar (2016). Innate immune system crosstalk: Eosinophils mediate immune modulation of dendritic cells through exosomes as shuttle vectors of miRNA (Submitted). (Dissertation, Graduate School for Cellular and Biomedical Sciences, University of Bern, Faculty of Medicine)


Djoumerska-Alexieva, Iglika; Roumenina, Lubka; Pashov, Anastas; Dimitrov, Jordan; Hadzhieva, Maya; Lindig, Sandro; Voynova, Elisaveta; Dimitrova, Petya; Ivanovska, Nina; Bockmeyer, Clemens; Stefanova, Zvetanka; Fitting, Catherine; Bläss, Markus; Claus, Ralf; von Gunten, Stephan; Kaveri, Srini; Cavaillon, Jean-Marc; Bauer, Michael; Vassilev, Tchavdar (2015). Intravenous Immunoglobulin with Enhanced Polyspecificity Improves Survival in Experimental Sepsis and Aseptic Systemic Inflammatory Response Syndromes. Molecular medicine, 21(1), p. 1. Feinstein Institute for Medical Research 10.2119/molmed.2014.00224

Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Schneider, Christoph; Smith, David F; Cummings, Richard D; Frias Boligan, Kayluz; Hamilton, Robert G; Bochner, Bruce S; Miescher, Sylvia; Simon, Hans-Uwe; Pashov, Anastas; Vassilev, Tchavdar; von Gunten, Stephan (2015). The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites. Science translational medicine, 7(269), 269ra1. American Association for the Advancement of Science 10.1126/scitranslmed.3010524

Cortinas-Elizondo, F.; von Gunten, Stephan (2015). MicroRNA-155: microtuning the allergic concert. Allergy, 70(9), pp. 1035-1036. Wiley-Blackwell 10.1111/all.12673


von Gunten, Stephan (2014). Protein-glycan interactions as targets of intravenous/subcutaneous immunoglobulin (IVIg/SCIg) preparations. Clinical and experimental immunology, 178(S1), pp. 151-152. Blackwell Scientific Publications 10.1111/cei.12550

Frias Boligan, Kayluz; Mesa, Circe; Fernandez, Luis Enrique; von Gunten, Stephan (2014). Cancer intelligence acquired (CIA): tumor glycosylation and sialylation codes dismantling antitumor defense. Cellular and molecular life sciences, 72(7), pp. 1231-1248. Springer 10.1007/s00018-014-1799-5

Wehrli, Marc; Cortinas-Elizondo, Fabiola; Hlushchuk, Ruslan; Daudel, Fritz; Villiger, Peter M.; Miescher, Sylvia; Zuercher, Adrian W.; Djonov, Valentin; Simon, Hans-Uwe; von Gunten, Stephan (2014). Human IgA Fc receptor FcαRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment. Journal of immunology, 193(11), pp. 5649-5659. American Association of Immunologists 10.4049/jimmunol.1400028

Stowell, Sean R.; Arthur, Connie M.; Mc Bride, Ryan; Berger, Oren; Razi, Nahid; Heimberg-Molinaro, Jamie; Rodrigues, Lilian C.; Gourdine, Jean-Philippe; Noll, Alexander J.; von Gunten, Stephan; Smith, David F.; Knirel, Yuriy A.; Paulson, James C.; Cummings, Richard D. (2014). Microbial glycan microarrays define key features of host-microbial interactions. Nature Chemical Biology, 10(6), pp. 470-476. Nature Publishing Group 10.1038/nchembio.1525

von Gunten, Stephan (2014). Targeting Siglecs: Neue potenzielle Strategien zur Immuntherapie entzündlicher oder maligner Erkrankungen. Leading Opinions. Hämatologie & Onkologie(2), pp. 34-36. Universimed

von Gunten, Stephan; Shoenfeld, Yehuda; Blank, Miri; Branch, Donald R.; Vassoöev, Tchavdar; Käsermann, Fabian; Bayy, Jagadeesh; Kaveri, Srini; Simon, Hans-Uwe (2014). IVIG pluripotency and the concept of Fc-sialylation: challenges to the scientist. Nature reviews - immunology, 14(5), pp. 349-350. Nature Publishing Group 10.1038/nri3401-c1

Jandus, Camilla; Frias Boligan, Kayluz; Chijioke, Obinna; Liu, He; Dahlhaus, Meike; Demoulins, Thomas; Schneider, Christoph; Wehrli, Marc; Hunger, Robert E.; Baerlocher, Gabriela M.; Simon, Hans-Uwe; Romero, Pedro; Münz, Christian; von Gunten, Stephan (2014). Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. Journal of clinical investigation, 124(4), pp. 1810-1820. American Society for Clinical Investigation 10.1172/JCI65899


von Gunten, Stephan; Wehrli, Marc; Simon, Hans-Uwe (2013). Cell death in immune thrombocytopenia: novel insights and perspectives. Seminars in hematology, 1(50), pp. 109-115. W.B. Saunders 10.1053/j.seminhematol.2013.03.016

Démoulins, Thomas; Bassi, Isabelle; Thomann-Harwood, Lisa; Jandus, Camilla; Simon, Hans-Uwe; von Gunten, Stephan; Mc Cullogh, Kenneth C (2013). Alginate-coated chitosan nanogel capacity to modulate the effect of TLR ligands on blood dendritic cells. Nanomedicine-Nanotechnology Biology and Medicine, 9(6), pp. 806-817. Elsevier 10.1016/j.nano.2013.01.002

von Gunten, Stephan; Schorer, Myriam Fabiola; Kollarik, M.; Beisswenger, C.; Lepper, P. M. (2013). Mechanisms and potential therapeutic targets in allergic inflammation: recent insights. Allergy, 68(12), pp. 1487-1498. Wiley-Blackwell 10.1111/all.12312


North, Simon J; von Gunten, Stephan; Antonopoulos, Aristotelis; Trollope, Alana; MacGlashan, Donald W; Jang-Lee, Jihye; Dell, Anne; Metcalfe, Dean D; Kirshenbaum, Arnold S; Bochner, Bruce S; Haslam, Stuart M (2012). Glycomic analysis of human mast cells, eosinophils and basophils. Glycobiology, 22(1), pp. 12-22. Oxford: Oxford University Press 10.1093/glycob/cwr089

von Gunten, Stephan; Kaufmann, Thomas (2012). Glucocorticoids 'on air'. Allergy, 67(2), pp. 144-6. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02778.x

von Gunten, S; Marsland, B J; von Garnier, C; Simon, D (2012). Update in clinical allergy and immunology. Allergy, 67(12), pp. 1491-500. Oxford: Wiley-Blackwell 10.1111/all.12067

von Gunten, Stephan; Simon, Hans-Uwe (2012). Granulocyte death regulation by naturally occurring autoantibodies. Advances in experimental medicine and biology, 750, pp. 157-172. Wien: Springer


Schaub, A; von Gunten, S; Vogel, M; Wymann, S; Rüegsegger, M; Stadler, B M; Spycher, M; Simon, H-U; Miescher, S (2011). Dimeric IVIG contains natural anti-Siglec-9 autoantibodies and their anti-idiotypes. Allergy, 66(8), pp. 1030-7. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02579.x

Casulli, Sarah; Topçu, Selma; Fattoum, Lakhdar; von Gunten, Stephan; Simon, Hans-Uwe; Teillaud, Jean-Luc; Bayry, Jagadeesh; Kaveri, Srini V.; Elbim, Carole (2011). A differential concentration-dependent effect of IVIg on neutrophil functions: relevance for anti-microbial and anti-inflammatory mechanisms. PLoS ONE, 6(10), e26469. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0026469

Grader-Beck, Thomas; Boin, Francesco; von Gunten, Stephan; Smith, David; Rosen, Antony; Bochner, Bruce S (2011). Antibodies recognising sulfated carbohydrates are prevalent in systemic sclerosis and associated with pulmonary vascular disease. Annals of the rheumatic diseases, 70(12), pp. 2218-24. London: BMJ Publishing Group 10.1136/ard.2011.153130

Jandus, Camilla; Simon, Hans-Uwe; von Gunten, Stephan (2011). Targeting siglecs--a novel pharmacological strategy for immuno- and glycotherapy. Biochemical pharmacology, 82(4), pp. 323-32. New York, N.Y.: Elsevier 10.1016/j.bcp.2011.05.018


von Gunten, Stephan; Simon, Hans-Uwe (2010). Cell death modulation by intravenous immunoglobulin. Journal of clinical immunology, 30 Suppl 1, S24-30. New York, N.Y.: Springer US; http://www.springer-ny.com 10.1007/s10875-010-9411-8


von Gunten, Stephan; Smith, David F; Cummings, Richard D; Riedel, Stefan; Miescher, Sylvia; Schaub, Alexander; Hamilton, Robert G; Bochner, Bruce S (2009). Intravenous immunoglobulin contains a broad repertoire of anticarbohydrate antibodies that is not restricted to the IgG2 subclass. Journal of allergy and clinical immunology, 123(6), 1268-76.e15. St. Louis, Mo.: Mosby 10.1016/j.jaci.2009.03.013

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