Gruppe von Gunten

Prof. Dr. Stephan von Gunten, MD, PhD, MME​

Gruppenmitglieder

former Gruppe Huwiler

ehemalige Gruppenmitglieder

Dr. Quentin Haas
Dr. Kayluz Frias Boligan
Dr. Stefanie Graeter
Dr. Fabiola Schorer
Dr. Christoph Schneider
Dr. Thomas Demoulins, Postdoc (2010-2012)
Dr. Dr. Camilla Jandus, Postdoc (2010-2012)
Dr. Dr. Marc Wehrli, MD Doktorand (2010-2013)  

Our laboratory is interested in molecular mechanisms that control inflammation and cancer. In particular, we focus on protein-carbohydrate interactions in the immune system and on anti-inflammatory effects mediated by Siglec receptors. Siglecs are carbohydrate-binding receptors (lectins) that have recently received particular attention in light of the capacity to mediate cell death, anti-proliferative effects, and inhibition of cellular activities. We recently identified natural autoantibodies within human intravenous immunoglobulin (IVIG) as endogenous Siglec receptor ligands. The group leader Dr. S. von Gunten is a participating investigator at the Consortium of Functional Glycomics (www.functionalglycomics.org), funded by the US National Institutes of Health (NIH), that aims at defining paradigms by which protein-carbohydrate interactions mediate cell communication. Our group has collaborations with scientists and clinicians from many international and local academic institutions, companies and hospitals.

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